Protein S abnormalities: A diagnostic nightmare

Preoperative Anxiety in Pediatric Population: Anesthesiologist"s Nightmare

Surgery in a child is one of the most important events of its life. Exposure to hospital environment including operating room away from own area of comfort, meeting with new peoples and visualising sick people in agony creates a significant impact on a child’s mind. Any unfavourable experience in this circumstance not only creates a fear towards medical systems for the lifetime but also sometim...

Protein C and protein S deficiency - practical diagnostic issues.

Protein C (PC) and protein S (PS) are vitamin K-dependent glycoproteins, that act as natural anticoagulants. The proteolytic activation of PC by thrombin occurs on the surface of endothelial cells and involves thrombomodulin and endothelial PC receptor. In the presence of PS, phospholipids and calcium, activated PC (APC) inactivates membrane bound factors V (FVa) and FVIIIa by their cleavage at...

A surgeon's nightmare: Complications.

OBJECTIVE Our study aimed to determine the physically and psychologically most difficult complication resulting in chronic discomfort and occurring sensationally in the postoperative period of operations performed frequently in the daily surgical routine. MATERIAL AND METHODS We performed a survey among surgeons who participated in the 19(th) National Surgery Congress. The questions were rela...

A father's worst nightmare.

A novel chimeric recombinant protein PDHB-P80 of Mycoplasma agalactiae as a potential diagnostic tool

The aim of this study was to construct, expression of a novel recombinant chimeric protein consisting of Pyruvate dehydrogenase beta subunit (PDHB) and high antigenic region of integral membrane lipoprotein P80 of Mycoplasma agalactiae as a potential diagnostic tool. The full-length sequence of pdhb and a portion of antigenic regions of P80 were selected and analyzed by CLC ma...